Descriptive Study: Attitude and Behaviour Regarding Oral Corticosteroid Use in Bebita Clinic Cicurug, Sukabumi in 2019

Audia Nizhma Nabila, Gladys Dwiani Tinovella Tubarad, Vanianissa Azzahra

Abstract


Background: Corticosteroids are derivatives of steroid hormones that have the effect of inhibiting the inflammatory response. Glucocorticoid is the type of corticosteroid that is easy to obtain and has a high anti-inflammatory effect. Therefore, glucocorticoids are often used in various therapies. However, the use of this drug should be monitored since its side effects can be harmful to the health as paralytic effects or even lethal effects. Purposes: This study aims to determine the behavior of using oral corticosteroids in patients at the Bebita Cicurug Clinic, Sukabumi. Methods: This is a descriptive quantitative research study. Data collection was done from September to December 2019. The respondents of this study were 96 subjects of Bebita Cicurug Clinic with a history of oral glucocorticoid usage. The data was taken using a questionnaire and medical records. Result: The most widely used glucocorticoid type is Methylprednisolone 4 mg and dexamethasone 0,5 mg. Overall, 89.6% of respondents used corticosteroids for a week or less. A total of 21.9% had tried to get corticosteroids without a prescription (self-medication), and all of them didn't get restricted on purchasing corticosteroids. Conclusion: In general, patients in this study had good behavior in using corticosteroids (using steroids according to a doctor's prescription), but 21.9% had tried to get corticosteroids without a prescription, and all of them didn't get restricted on purchasing corticosteroids. Doctors and health workers must clearly explain prescribed drugs' benefits and side effects, especially in patients with chronic diseases. Then ensure that the patient has understood the benefits and side effects of the medications used.


Keywords


corticosteroid use; oral glucocorticoids; self-medication

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References


Triakoso N. Penggunaan Kortikosteroid dan Non-Steroid Anti-Inflammatory Drug. 2008.

Gunawan S. Farmakologi dan Terapi. 6th ed. Jakarta: Departemen Farmakologi dan Terapeutik FKUI; 2016.

BPOM. Peraturan Badan Pengawas Obat dan Makanan Nomor 23 Tahun 2019 Tentang Persyaratan Teknis Bahan Kosmetik. Vol. 2010, BPOM Republik Indonesia. 2019. p. 1–16.

Widyawati E, Rusdi B, Maulana T. Identifikasi Kandungan Kortikosteroid (Deksametason, Fenilbutason, Dan Prednison) Dalam Kandungan Jamu Pegal Linu Yang Beredar Di Empat Pasar Kota Bandung 1,2,3. In: Prosiding Penelitian SPeSIA Unisba. 2013. p. 525–30.

WHO. WHO_DAP_98.13.pdf. 2000.

Lei X, Jiang H, Liu C, Ferrier A, Mugavin J. Self-Medication Practice and Associated Factors among Residents in Wuhan, China. Int J Environ Res Public Health. 2018 Jan;15(1).

Ahmed SM, Sundby J, Aragaw YA, Abebe F. Self-Medication and Safety Profile of Medicines Used among Pregnant Women in a Tertiary Teaching Hospital in Jimma, Ethiopia: A Cross-Sectional Study. Vol. 17, International Journal of Environmental Research and Public Health . 2020.

Kemenkes RI. Profil Kesehatan RI 2015 [Internet]. Profil Kesehatan Indonesia Tahun 2015. 2015. 1–125 p. Available from: https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-Tahun-2015.pdf

Helal RM, Abou-ElWafa HS. Self-Medication in University Students from the City of Mansoura, Egypt. Gerber LM, editor. J Environ Public Health [Internet]. 2017;2017:9145193. Available from: https://doi.org/10.1155/2017/9145193

Dayani H. Profil Penggunaan Obat Kortikosteroid di Puskesmas Kabupaten Serdang Bedagai dan Kota Tebing Tinggi. Universitas Sumatera Utara; 2020.

Mahdy A, Hussain N, Khalidi D, Said A. Knowledge, attitude, and practice analysis of corticosteroid use among patients: A study based in the United Arab Emirates. Natl J Physiol Pharm Pharmacol [Internet]. 2017;7(6):562–8. Available from: http://www.scopemed.org/fulltextpdf.php?mno=252653

Hoes JN, Jacobs J, Verstappen S, Bijlsma J, van der Heijden G. Adverse events of low- to medium-dose oral glucocorticoids in inflammatory diseases: A meta-analysis. Ann Rheum Dis. 2009 Dec 1;68:1833–8.

Schimer B, Parker K. Hormon Adrenokortikotropik; Adrenokortikosteroid dan Analog Sintetisnya; Inhibitor Sintesis dan Kerja Hormon-Hormon Adrenokortikal. In: Goodman & Gilman: Dasar Farmakologi Terapi. EGC; 2012.

Waljee AK, Rogers MAM, Lin P, Singal AG, Stein JD, Marks RM, et al. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study. BMJ [Internet]. 2017 Apr 12;j1415. Available from: https://www.bmj.com/lookup/doi/10.1136/bmj.j1415

Pamuji A. Faktor Pengetahuan, Sikap, dan Perilaku yang Mempengaruhi Konsumen Dalam Memilih Obat Generik dan Obat Bermerek Dalam Swamedikasi di Kabupaten Banyumas. Universitas Muhammadiyah Purwokerto; 2017.

M. Rifqi Rokhman, Mentari Widiastuti, Satibi, Ria Fasyah Fatmawati, Na’imatul Munawaroh YAP. Penyerahan Obat Keras Tanpa Resep Di Apotek. Vol 7 Nomor 3 – Sept 2017 p-ISSN. 2018;7(3):115–24.

Siahaan S, Usia T, Pujiati S, Tarigan I, Murhandini S, Isfandari S, et al. Pengetahuan, Sikap, dan Perilaku Masyarakat dalam Memilih Obat yang Aman di Tiga Provinsi di Indonesia. J Kefarmasian Indones [Internet]. 2017 Aug 22;7(2 SE-Articles). Available from: https://ejournal2.litbang.kemkes.go.id/index.php/jki/article/view/3492

Rahayu KE. Faktor yang Mempengaruhi Perilaku Masyarakat dalam Membeli Obat di Warung. Universitas Ngudi Waluyo; 2020.

Kristina, S.A., Prabandari, Y.S., Sudjaswadi R. Perilaku pengobatan sendiri yang rasional pada masyarakat. Perilaku pengobatan sendiri yang rasional pada Masy [Internet]. 2007;23(4):208–18. Available from: http://dx.doi.org/10.1016/j.phrs.2017.02.008

Yao T-C, Wang J-Y, Chang S-M, Chang Y-C, Tsai Y-F, Wu AC, et al. Association of Oral Corticosteroid Bursts With Severe Adverse Events in Children. JAMA Pediatr [Internet]. 2021 Jul 1;175(7):723–9. Available from: https://doi.org/10.1001/jamapediatrics.2021.0433

Dinsen S, Baslund B, Klose M, Rasmussen AK, Friis-Hansen L, Hilsted L, et al. Why glucocorticoid withdrawal may sometimes be as dangerous as the treatment itself. Eur J Intern Med. 2013 Dec;24(8):714–20.

Savas M, Vinkers CH, Rosmalen JGM, Hartman CA, Wester VL, van den Akker ELT, et al. Systemic and Local Corticosteroid Use Is Associated with Reduced Executive Cognition, and Mood and Anxiety Disorders. Neuroendocrinology [Internet]. 2020;110(3–4):282–91. Available from: https://www.karger.com/DOI/10.1159/000501617

Hardy J, Haywood A, Rickett K, Sallnow L, Good P. Practice review: Evidence-based quality use of corticosteroids in the palliative care of patients with advanced cancer. Palliat Med [Internet]. 2021 Jan 27;35(3):461–72. Available from: https://doi.org/10.1177/0269216320986717




DOI: https://doi.org/10.24853/mmj.3.1.10-18

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