Faktor Risiko pada Kesintasan Pasien Geriatri dengan COVID-19 di RS Urip Sumoharjo Bandarlampung

Sekar Ayu Wirawan, Paskalis Andrew Gunawan

Abstract


COVID-19 adalah penyakit pernapasan oleh SARS-CoV-2, virus corona varian baru yang ditemukan tahun 2019. Pasien COVID-19 dapat mengalami sakit berat ataupun meninggal pada usia berapapun karena beratnya penyakit dipengaruhi oleh kondisi medis dan usia pasien. Tujuan penelitian ini adalah mengetahui faktor risiko yang memengaruhi kesintasan pasien geriatri COVID-19, mengingat usia lanjut diketahui sebagai salah satu faktor risiko terjadinya manifestasi klinis yang berat bahkan kematian. Metode yang digunakan adalah desain penelitian analitik potong lintang, Sampel diambil secara purposive non-random sampling dari data rekam medis pasien geriatri COVID-19 di RS Urip Sumoharjo Bandarlampung periode 2021. Data tersebut kemudian dianalisis dengan metode chi-square, independent t-test, dan logistic regression menggunakan aplikasi olah data SPSS. Hasil penelitian dari 125 pasien COVID-19 berusia 60 tahun ke atas, diketahui sebanyak 48,8% meninggal. Melalui analisis bivariat, didapatkan beberapa faktor yang bermakna (p-value <0,05) terhadap kesintasan pasien geriatri COVID-19 diantaranya gejala sesak napas, lama rawat, kadar SpO2, hitung leukosit dan limfosit, serta temuan radiologi toraks. Selanjutnya, menggunakan analisis multivariat, diketahui bahwa terdapat tiga faktor risiko yang memiliki kemaknaan dengan kesintasan pasien. Kesimpulan yang didapatkan adalah gejala demam, lama rawat, dan kadar SpO2 merupakan tiga faktor risiko yang paling berperan terhadap kesintasan pasien geriatri COVID-19 di RS Urip Sumoharjo Bandarlampung.


Keywords


COVID-19, lanjut usia, geriatri, faktor risiko, kesintasan

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References


Centers for Disease Control and Prevention. Disease or condition of the week: COVID-19 [Internet]. 2021 [cited 2021 Sep 15]. Available from: https://www.cdc.gov/dotw/covid-19/index.html

World Health Organization. Coronavirus disease [Internet]. 2021 [cited 2021 Sep 15]. Available from: https://www.who.int/health-topics/coronavirus

Cascella M, Rajnik M, Cuomo A, Dulebohn SC, di Napoli R. Features, Evaluation and Treatment Coronavirus (COVID-19) - StatPearls - NCBI Bookshelf. StatPearls. 2020.

Dhama K, Patel SK, Kumar R, Rana J, Yatoo MI, Kumar A, et al. Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond. Vol. 8, Frontiers in Public Health. Frontiers Media S.A.; 2020.

KPCPEN STPC 19. Peta sebaran [Internet]. 2021 [cited 2023 Sep 15]. Available from: https://covid19.go.id/peta-sebaran

Subdirektorat Statistik Pendidikan dan Kesejahteraan Sosial. Statistik Penduduk Lanjut Usia 2020. 2020.

Perrotta F, Corbi G, Mazzeo G, Boccia M, Aronne L, D’Agnano V, et al. COVID-19 and the elderly: insights into pathogenesis and clinical decision-making. Vol. 32, Aging Clinical and Experimental Research. Springer Science and Business Media Deutschland GmbH; 2020. p. 1599–608.

Yanez ND, Weiss NS, Romand JA, Treggiari MM. COVID-19 mortality risk for older men and women. BMC Public Health. 2020 Dec 1;20(1).

Wang L, He W, Yu X, Hu D, Bao M, Liu H, et al. Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up. Journal of Infection. 2020 Jun 1;80(6):639–45.

Susilo A, Martin Rumende C, Pitoyo CW, Djoko Santoso W, Yulianti M, Sinto R, et al. Tinjauan pustaka [Internet]. Vol. 7, Jurnal Penyakit Dalam Indonesia |. 2020. Available from: https://www.ncbi.nlm.nih.gov/nuccore/

Dres M, Hajage D, Lebbah S, Kimmoun A, Pham T, Béduneau G, et al. Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study: Prognosis of COVID-19 elderly critically ill patients in the ICU. Ann Intensive Care. 2021 Dec 1;11(1).

Leung C. Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China. Vol. 188, Mechanisms of Ageing and Development. Elsevier Ireland Ltd; 2020.

Gómez-Belda AB, Fernández-Garcés M, Mateo-Sanchis E, Madrazo M, Carmona M, Piles-Roger L, et al. COVID-19 in older adults: What are the differences with younger patients? Geriatr Gerontol Int. 2021 Jan 1;21(1):60–5.

U.S. National Library of Medicine. Study of lymphopenia as a specific biomarker or prognostic risk factor for disease severity in elderly patients with COVID-19 [Internet]. 2021 [cited 2022 May 22]. Available from: https://clinicaltrials.gov/ct2/show/record/NCT04800731?view=record

Lee J, Park SS, Kim TY, Lee DG, Kim DW. Lymphopenia as a biological predictor of outcomes in COVID-19 patients: A nationwide cohort study. Cancers (Basel). 2021;13(3).

Al-Zahrani J. SARS-CoV-2 associated COVID-19 in geriatric population: A brief narrative review. Vol. 28, Saudi Journal of Biological Sciences. Elsevier B.V.; 2021. p. 738–43.

Rehatta NM, Sari D, Gadjah U, Mayang M, Lestari I. Comorbidities and COVID-19 Status Inuence the Survival Rate of Geriatric Patients in Intensive Care Units: a Prospective Cohort Study From the Indonesian Society of Anaesthesiology and Intensive Therapy. 2021; Available from: https://doi.org/10.21203/rs.3.rs-969262/v1

Jiang Y, Abudurexiti S, An MM, Cao D, Wei J, Gong P. Risk factors associated with 28-day all-cause mortality in older severe COVID-19 patients in Wuhan, China: a retrospective observational study. Sci Rep. 2020 Dec 1;10(1).

Azwar MK, Setiati S, Rizka A, Fitriana I, Rizny Saldi SF, Safitri ED. Clinical Profile of Elderly Patients with COVID-19 Hospitalized in Indonesia’s National General Hospital. Vol. 52, Acta Med Indones-Indones J Intern Med •. 2020.

Singhal S, Kumar P, Singh S, Saha S, Dey AB. Clinical features and outcomes of COVID-19 in older adults: a systematic review and meta-analysis. BMC Geriatr. 2021 Dec 1;21(1).

Neumann-Podczaska A, Al-Saad SR, Karbowski LM, Chojnicki M, Tobis S, Wieczorowska-Tobis K. COVID 19 - Clinical picture in the elderly population: A qualitative systematic review. Vol. 11, Aging and Disease. International Society on Aging and Disease; 2020. p. 988–1008.




DOI: https://doi.org/10.24853/jkk.19.1.1-10

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